| Commissioner | Distr | Appt | Apptd By | 1st Term | 2nd Term |
| Pardis Mahdavi | 1st | September 2018 | Gov. Hickenlooper | 2018-2022 | |
| John Anderson | 3rd | December 2013 | Gov. Hickenlooper | 2013-2015 | 2016-2018 |
| Maia Babbs | 7th | June 2015 | Gov. Hickenlooper | 2016-2019 | |
| Mary Beth Buescher | 3rd | July 2016 | Gov. Hickenlooper | 2016-2020 | |
| Luis Colon | 4th | July 2013 | Gov. Hickenlooper (r) | 2013-2017 | 2017-2021 |
| Renny Fagan | 7th | July 2015 | Gov. Hickenlooper | 2016-2019 | |
| Cassie Gannett | 5th | July 1, 2016 | Gov. Hickenlooper | 2016-2020 | |
| Jeanette Garcia | 3rd | Aug 2011 | Gov. Hickenlooper | 2011-2015 | 2016-2019 |
| Vanecia Kerr | 6th | October 2014 | Gov. Hickenlooper | 2015-2018 | 2018-2022 |
| Tom McGimpsey | 2nd | July 2015 | Gov. Hickenlooper | 2016-2017 | 2017-2021 |
| Dr. Monte Moses | 6th | Aug 2011 | Gov. Hickenlooper | 2011-2015 | 2016-2019 |
| Paula Sandoval | 1st | January 2015 | Gov. Hickenlooper | 2015-2018 | |
| Richard Kaufman | 6th | Aug 2010 | Gov. Ritter | 2010-2012 | 2012-2016 |
| Kevin Reimer | 3rd |
May 2013 |
Gov. Hickenlooper (r) | 2013-2015 | |
| David L. Edwards | 4th | Nov 2009 | Gov. Ritter | 2009-2012 (p) | - |
| Regina M. Rodriguez | 7th | Nov 2009 | Gov. Ritter | 2009-2013 | - |
| Happy Haynes | 1st | Sep 2008 | Gov. Ritter (r) | 2010-2014 | - |
| Hereford Percy | 7th | Aug 2008 | Gov. Ritter (r) | 2008-2011 | 2011-2015 |
| BJ Scott | 5th | Jun 2008 | Gov. Ritter | 2008-2012 | 2012-2016 |
| Jill L. Brake | 3rd | Jul 2007 | Gov. Ritter | 2007-2011 | - |
| Patricia L. Pacey | 2nd | Jul 2007 | Gov. Ritter | 2007-2011 | 2011-2015 |
| Mike Plachy | 6th | Jul 2007 | Gov. Ritter (r) | 2008-2010 | - |
| James T. Polsfut | 7th | May 2007 | Gov. Ritter (r) | 2007-2010 | 2010-2014 |
| Joel Rosenstein | 1st | Nov 2006 | Gov. Owens | 2006-2008 (p) | - |
| Carrie Besnette | 1st | Nov 2006 | Gov. Owens | 2006-2007 (p) | - |
| Edward Robinson | 6th | Jul 2005 | Gov. Owens | 2005-2009 | - |
| Richard Ramirez | 4th | Jul 2005 | Gov. Owens | 2005-2009 | - |
| Joel Farkas | 6th | May 2005 | Gov. Owens | 2005-2006 (p) | - |
| Mike Feeley | 7th | Mar 2004 | Gov. Owens | 2004-2005 (p) | - |
| Greg C. Stevinson | 6th | Feb 2004 | Gov. Owens | 2003-2007 | 2007-2011 |
| Richard Garcia | 2nd | Oct 2003 | Gov. Owens | 2003-2007 | - |
| Gully Stanford | 1st | Jan 2003 | Gov. Owens | 2003 (p) | - |
| Terry Farina | 3rd | Jul 2002 | Gov. Owens | 2002-2006 | - |
| Judy Weaver | 3rd | Nov 2001 | Gov. Owens (r) | 2003-2007 | - |
| Judith Altenberg | 6th | Jul 2001 | Gov. Owens (r) | 2002-2006 | - |
| Preslano Montoya | 4th | Jul 2001 | Gov. Owens | 2001-2005 | - |
| Kelli McGregor | 3rd | Jul 2001 | Gov. Owens | 2001 (p) | - |
| James Stewart | 5th | Jul 2000 | Gov. Owens | 2000-2004 | 2004-2008 |
| Ray Baker | 7th | Jul 2000 | Gov. Owens | 2000-2004 | 2004-2008 |
| Peggy Lamm | 2nd | Jul 1999 | Gov. Owens | 1999-2003 | |
| Ralph J. Nagel | 5th | Jul 1999 | Gov. Owens | 1999-2003 | - |
| Dean Quamme | 3rd | Jul 1999 | Gov. Owens | 1999-2003 | 2003-2007 |
| Bill Vollbracht | 1st | Jul 1999 | Gov. Owens (r) | 1999-2003 | 2004 |
| Marion S. Gottesfeld | 1st | Feb 1999 | Gov. Owens | 1999-2001 (p) | - |
| Robert A. Hessler | 4th | Jul 1997 | Gov. Romer | 1997-2001 | - |
| J. Lamar Allen | 5th | Jul 1996 | Gov. Romer | 1996-2000 | - |
| David E. Greenberg | 6th | Dec 1992 | Gov. Romer | 1993-1997 | 1997-2001 |
| Alexander E. Bracken | 2nd | Jul 1992 | Gov. Romer | 1996-2000 | - |
| (p) - Partial Term; (r) - Replaced Commissioner | |||||
| Commissioners serving prior to 2000 | |||||
| Lawrence Atler | |||||
| Marshall Crawford | |||||
| Brian Hall | |||||
| Robert Hawkins | |||||
| Christine Johnson | |||||
| Betty Marvel | |||||
| Thomas Norton | |||||
| Gail Schwartz | |||||
| Tim Waters | |||||
